David J. Pepperl, PhD

David J. Pepperl, PhD

Group Leader
Nonclinical Development

David Pepperl, PhD, is a pharmacologist and toxicologist with experience in the early stage development of biologic products. Prior to joining Biologics Consulting, David served as toxicologist and preclinical development scientist at TherImmune Research Corporation, where he drafted nonclinical development plans, authored nonclinical sections of regulatory submissions and managed preclinical development programs for clients.

Dr. Pepperl’s early work focused on in vitro and cell biological models of drug action, safety and signaling. During his tenure at Biologics Consulting, he has designed and overseen numerous nonclinical development programs for a variety of biologic products, including cell and gene therapies, vaccines, blood products, monoclonal antibodies and protein therapeutics as well as small molecules. In addition to protocol and study report reviews, Dr. Pepperl routinely performs nonclinical safety assessments, and both authors and reviews development plans for a diverse array of drugs and biologic products. He has written numerous nonclinical sections of pre-INDs, INDs and CTDs behalf of clients, and routinely assists sponsors with FDA meetings and other interactions with regulatory interactions. Dr. Pepperl has also worked closely with sponsors to source and manage bot non-GLP and GLP safety studies at contract research organizations (CROs) and routinely performs GLP compliance inspections of behalf of clients.

David received his BS in Biochemistry from Michigan State University in 1988, and his PhD in Pharmacology & Toxicology from the University of Arizona in 1994 with an emphasis on the pharmacology and signaling of G-protein coupled adrenergic receptors. He completed post-doctoral work at Pharmacia and Parke-Davis Pharmaceuticals. Dr. Pepperl joined Biologics Consulting as a Senior Consultant in January of 2004 and has served as Pharm/Tox team leader since 2015. He currently resides with his family in Montgomery Village, Maryland, and enjoys cycling, fitness and hiking.


Education

PhD, Pharmacology and Toxicology, University of Arizona, Tucson, AZ (1994)

BS, Biochemistry, Michigan State University, East Lansing, MI (1988)